More information News Career opportunities

Welcome

Envoy Therapeutics is a new company, and we haven’t created our website yet. Instead, we’ve been focused on discovering new medicines for people suffering from neurological and psychiatric diseases. Please check back in the future if you want to see our website.

Meanwhile, with exclusive rights to a powerful technology developed at Rockefeller University, and an exceptional team of neuroscientists, we are beginning to make rapid and efficient progress toward our goal of bringing new medicines to market.

Our technology combines innovative genetic engineering with new molecular biology techniques for labeling and extracting the protein-making components of specific types of cells. This technology is enabling our scientists to make breakthrough discoveries by identifying and measuring proteins that are specifically produced by cells that are important to a particular disease without requiring the isolation of those cells. Capability like this has never before existed.

We’re Focused On the Brain

Our technology is especially powerful in tissues of the brain, where up to a thousand cell types are intermingled and where until now, therapeutically modulating the activity of a specific cell type has been prevented by the inability to determine which proteins are uniquely expressed by that cell type. Our technology enables scientists to compare both the assortment and the levels of proteins produced by certain types of cells with other types of cells, and to understand precisely in specific cell types how genes and proteins are expressed differently in response to different drugs.

We have already used our technology on a large scale to discover proteins that are highly produced in cell types known to be important to five diseases: schizophrenia, Parkinson’s Disease, Alzheimer’s Disease, drug addiction and epilepsy. Many of these identified proteins belong to protein classes whose activity has been demonstrated to be modifiable by drugs. As a result, the manipulation of these new “target proteins" holds great promise for providing the mechanisms by which new drugs will help patients in the future.

In addition to these targets that we have already discovered, we have resources in place that will enable us to pursue targets for seven additional diseases: anxiety, depression, sleep, pain, obesity, autism and attention deficit hyperactivity disorder.

Founding Team

Envoy has three highly recognized scientific founders, including Nobel Laureate and National Academy of Sciences member Paul Greengard, PhD.; Howard Hughes Medical Institute Investigator Nathaniel Heintz; and National Academy of Sciences member and Howard Hughes Medical Institute Investigator, Jeffrey Friedman, M.D., PhD, who was also a scientific founder of Millennium Pharmaceuticals.

These scientific founders bring great expertise in disciplines vital to Envoy’s missions including the biochemical regulation of brain cells and neurotransmitter receptors, the molecular mechanisms involved in obesity, body weight, appetite and fat storage, and the engineering of bacteria artificial chromosomes (BACs) by homologous recombination and transgenic technology. Our fourth founder and CEO, Brad Margus, is a seasoned executive with a strong track record in starting and building science based organizations, protecting new discoveries, raising capital, and partnering repeatedly with many of the world’s largest pharmaceutical companies.

Our Business

We expect to create substantial shareholder value by:

· identifying new, medically important, target proteins,

· building a portfolio of promising, proprietary new drugs that modulate those proteins and fill unmet medical needs,

· demonstrating repeatedly the enormous power of our technology platform, and

· delivering successful results with a select number of partnerships with global pharmaceutical companies.

We’re passionate about creating and exploiting our completely new and unique drug discovery engine.

For more information, please email: info@envoytherapeutics.com.

Envoy Therapeutics, Inc.

555 Heritage Drive

Jupiter, Florida 33458

Telephone: 561.210.7705